YMC Hydrosphere C18

YMC Hydrosphere C18 Analytical HPLC Columns

The separation of polar compounds in many cases requires highly aqueous mobile phase conditions to achieve sufficient retention on the stationary phase. Conventional reversed phase selectivities do not give reproducible results under these conditions mainly due to the collapse of the C18 chains. Hydrosphere C18 has been developed, on the ultra pure silica support of the ProFamily, to be stable in 100% aqueous eluents.

For ultra-fast LC applications YMC-Ultra HT Hydrosphere C18 with 2 µm particle size provides the optimal selectivity for the separation of highly polar compounds.

YMC Hydrosphere C18

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Features
  • Stable under the use of 100% aqueous eluent
  • "Hydrophilic" C18 surface for enhanced polar recognition
  • No need for ion pair reagents
  • Based on highly inert, ultrapure, pH neutral silica
  • Specifically designed for pharmaceutical and biotechnology R&D
Specifications
  Hydrosphere C18
Modification C18 (USP L1)
Particle size  2, 3, 5 µm
Pore size  12 nm / 120 Å
Surface area 330 m2/g
Carbon load 12%
pH range 2 - 8
AQ stability 100% H2O eluents
Literature